NAMI-A is highly cytotoxic toward leukaemia cell lines: evidence of inhibition of KCa 3.1 channels-Reference-Cited by-同舟云学术

NAMI-A is highly cytotoxic toward leukaemia cell lines: evidence of inhibition of KCa 3.1 channels

Published:2014 Issue:32 Volume:43 Page:12150-12155
ISSN:1477-9226
Container-title:Dalton Trans.
language:en
Short-container-title:Dalton Trans.

Author:

Pillozzi Serena¹²³,Gasparoli Luca¹²³,Stefanini Matteo¹²³,Ristori Mirco¹²³,D'Amico Massimo¹²³,Alessio Enzo⁴⁵⁶,Scaletti Federica⁷²⁸,Becchetti Andrea⁹¹⁰¹¹,Arcangeli Annarosa¹²³,Messori Luigi⁷²⁸

Affiliation:

1. Department of Experimental and Clinical Medicine

2. University of Florence

3. 50134 Firenze, Italy

4. Department of Chemical Sciences

5. University of Trieste

6. 34127 Trieste, Italy

7. Department of Chemistry “Ugo Schiff”

8. 50019 Sesto Fiorentino (FI), Italy

9. Department of Biotechnologies and Biosciences

10. University of Milano-Bicocca

11. Milan, Italy

Abstract

The anticancer ruthenium(iii) complex NAMI-A induces potent and unexpected cytotoxic effects in leukaemia cells causing selective inhibition of KCa 3.1 channels.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/DT/C4DT01356E

Reference37 articles.

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4. I. Bratsos , T.Gianferrara , E.Alessio , C. G.Hartinger , M. A.Jakupec and B. K.Keppler , in Bioinorganic Medicinal Chemistry , ed. E. Alessio , Wiley-VCH , Weinheim , 2011 , pp. 151–174

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