Sensitive and selective detection of the p53 gene based on a triple-helix magnetic probe coupled to a fluorescent liposome hybridization assembly via rolling circle amplification-Reference-Cited by-同舟云学术

Sensitive and selective detection of the p53 gene based on a triple-helix magnetic probe coupled to a fluorescent liposome hybridization assembly via rolling circle amplification

Published:2017 Issue:19 Volume:142 Page:3598-3604
ISSN:0003-2654
Container-title:The Analyst
language:en
Short-container-title:Analyst

Author:

Li Xia¹²³⁴⁵,Song Juan¹²³⁴,Xue Qingwang¹²³⁴^ORCID,Zhao Haiyan⁵⁶⁷⁸⁹,Liu Min¹²³⁴,Chen Baoli¹²³⁴,Liu Yun¹²³⁴,Jiang Wei⁵⁶⁷⁸⁹^ORCID,Li Chen-zhong¹²³⁴¹⁰^ORCID

Affiliation:

1. Department of Chemistry

2. Liaocheng University

3. Liaocheng 252059

4. China

5. Key Laboratory for Colloid and Interface Chemistry of Education Ministry

6. School of Chemistry and Chemical Engineering

7. Shandong University

8. 250100 Jinan

9. P.R. China

10. Nanobioengineering/Bioelectronics Laboratory

Abstract

Developing a sensitive and selective sensing platform for the p53 gene and its mutation analysis is essential and may aid in early cancer screening and assessment of prognosis.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/AN/C7AN01255A

Reference34 articles.

1. Rapid and sensitive detection of point mutations and DNA polymorphisms using the polymerase chain reaction

2. Acute DNA damage activates the tumour suppressor p53 to promote radiation-induced lymphoma

3. Dual-Targeting Nanovesicles for In Situ Intracellular Imaging of and Discrimination between Wild-type and Mutant p53