Bicyclic imidazole-4-one derivatives: a new class of antagonists for the orphan G protein-coupled receptors GPR18 and GPR55-Reference-Cited by-同舟云学术

Bicyclic imidazole-4-one derivatives: a new class of antagonists for the orphan G protein-coupled receptors GPR18 and GPR55

Published:2014 Issue:5 Volume:5 Page:632-649
ISSN:2040-2503
Container-title:Med. Chem. Commun.
language:en
Short-container-title:Med. Chem. Commun.

Author:

Rempel V.¹²³⁴,Atzler K.¹²³⁴,Behrenswerth A.¹²³⁴,Karcz T.¹²³⁴⁵,Schoeder C.¹²³⁴,Hinz S.¹²³⁴,Kaleta M.⁵⁶⁷⁸,Thimm D.¹²³⁴,Kiec-Kononowicz K.⁵⁶⁷⁸,Müller C. E.¹²³⁴

Affiliation:

1. PharmaCenter Bonn

2. Pharmaceutical Institute

3. Pharmaceutical Chemistry I

4. D-53121 Bonn, Germany

5. Department of Technology and Biotechnology of Drugs

6. Jagiellonian University Medical College

7. Faculty of Pharmacy

8. Kraków, Poland

Abstract

GPR18 and GPR55 are orphan G protein-coupled receptors (GPCRs) that interact with certain cannabinoid (CB) receptor ligands.

Publisher

Royal Society of Chemistry (RSC)

Subject

Pharmaceutical Science,Biochemistry,Drug Discovery,Molecular Medicine,Pharmacology,Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/MD/C3MD00394A

Reference55 articles.

1. Functional Characterization and Analgesic Effects of Mixed Cannabinoid Receptor/T-Type Channel Ligands

2. Off-Target Cannabinoid Effects Mediated by GPR55

3. The therapeutic potential of novel cannabinoid receptors

4. CANNABINOID RECEPTORS AS THERAPEUTIC TARGETS

5. The Endocannabinoid System as an Emerging Target of Pharmacotherapy

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