Dynamic analysis of Porphyromonas gingivalis invasion into blood capillaries during the infection process in host tissues using a vascularized three-dimensional human gingival model-Reference-Cited by-同舟云学术

Dynamic analysis of Porphyromonas gingivalis invasion into blood capillaries during the infection process in host tissues using a vascularized three-dimensional human gingival model

Published:2021 Issue:19 Volume:9 Page:6574-6583
ISSN:2047-4830
Container-title:Biomaterials Science
language:en
Short-container-title:Biomater. Sci.

Author:

Sasaki Naoko¹,Takeuchi Hiroki²,Kitano Shiro¹³,Irie Shinji¹³,Amano Atsuo²^ORCID,Matsusaki Michiya¹⁴^ORCID

Affiliation:

1. Joint Research Laboratory (TOPPAN) for Advanced Cell Regulatory Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan

2. Department of Preventive Dentistry, Osaka University Graduate School of Dentistry, 1-8 Yamadaoka, Suita, Osaka 565-0871, Japan

3. TOPPAN PRINTING CO., LTD, Japan

4. Department of Applied Chemistry, Graduate School of Engineering, Osaka University, 2-1 Yamadaoka, Suita, Osaka 565-0871, Japan

Abstract

Reconstruction of a vascularized gingival 3D model which can be invaded by P. gingivalis through blood capillaries (HGF: human gingival fibroblast, HUVEC: human umbilical vein endothelial cell, IHGE cell: immortalized human gingival epithelial cell).

Funder

Japan Society for the Promotion of Science

Japan Agency for Medical Research and Development

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering

Link

http://pubs.rsc.org/en/content/articlepdf/2021/BM/D1BM00831E

Reference50 articles.

1. Diabetes mellitus and inflammatory periodontal diseases

2. Porphyromonas gingivalis in Alzheimer’s disease brains: Evidence for disease causation and treatment with small-molecule inhibitors