Poly(N-(2-hydroxypropyl)methacrylamide)–valproic acid conjugates as block copolymer nanocarriers-Reference-Cited by-同舟云学术

Poly(N-(2-hydroxypropyl)methacrylamide)–valproic acid conjugates as block copolymer nanocarriers

Published:2017 Issue:34 Volume:8 Page:4983-4987
ISSN:1759-9954
Container-title:Polymer Chemistry
language:en
Short-container-title:Polym. Chem.

Author:

Alfurhood Jawaher A.¹²³⁴⁵,Sun Hao¹²³⁴⁵^ORCID,Kabb Christopher P.¹²³⁴⁵^ORCID,Tucker Bryan S.¹²³⁴⁵,Matthews James H.⁶⁷⁸⁴⁵,Luesch Hendrik⁶⁷⁸⁴⁵,Sumerlin Brent S.¹²³⁴⁵^ORCID

Affiliation:

1. George & Josephine Butler Polymer Research Laboratory

2. Center for Macromolecular Science & Engineering

3. Department of Chemistry

4. University of Florida

5. Gainesville

6. Department of Medicinal Chemistry

7. Center for Natural Products

8. Drug Discovery and Development (CNPD3)

Abstract

We report nanoassemblies based on block copolymers of N-(2-hydroxypropyl)methacrylamide (HPMA) in which drug cleavage enhances the biological compatibility of the original polymer carrier by regeneration of HPMA units.

Funder

National Institutes of Health

Division of Materials Research

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Polymers and Plastics,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2017/PY/C7PY00196G

Reference44 articles.

1. Design of polymeric nanoparticles for biomedical delivery applications

2. Polymer conjugates as anticancer nanomedicines