FePt nanoparticles: a novel nanoprobe for enhanced HeLa cells sensitivity to chemoradiotherapy

Author:

Bao Zhirong1234,He Mingyang5264,Quan Hong1234,Jiang Dazhen1234,Zheng Yanhong789104,Qin Wenjing1234,Zhou Yunfeng11124,Ren Feng1234,Guo Mingxiong5264,Jiang Changzhong1234

Affiliation:

1. Key Laboratory of Artificial Micro- and Nano-Structures of the Ministry of Education and Center for Electronic Microscopy and Department of Physics

2. Wuhan University

3. Wuhan 430072

4. PR China

5. College of Life Sciences

6. 430072 Wuhan

7. Oncology Department

8. Tongji Hospital

9. Tongji Medical College

10. Huazhong University of Science & Technology

11. Department of Radiation and Medical Oncology

12. Zhongnan Hospital of Wuhan University

Abstract

The present work exhibited high therapeutic efficacy of FePt nanoparticles in combination with radiotherapy without apparent cytotoxicity, suggesting the potential of FePt nanoparticles as a promising nanoprobe in improving the outcome of tumor chemoradiotherapy.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

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