Lactobacillus casei LC89 exerts antidiabetic effects through regulating hepatic glucagon response and gut microbiota in type 2 diabetic mice

Author:

Zhang Yongli1,Wu Tao1ORCID,Li Wen1,Zhao Yunjiao1,Long Hairong12,Liu Rui1,Sui Wenjie1,Zhang Min13

Affiliation:

1. Key Laboratory of Food Nutrition and Safety, Ministry of Education & Tianjin Key Laboratory of Food Nutrition and Safety, Food Biotechnology Engineering Research Center of Ministry of Education, Tianjin University of Science & Technology, Tianjin 300457, China

2. Guangxi Botanical Garden of Medicinal Plants, Nanning, Guangxi, 530023, China

3. Tianjin Agricultural University, Tianjin 300384, China

Abstract

Lactobacillus casei LC89 exhibits remarkable anti-diabetic effects by inhibiting hepatic glucagon action and reshaping the gut microbiota, and might be considered as a dietary supplement to regulate glucose metabolism.

Funder

State Key Laboratory of Food Nutrition and Safety

Science and Technology Major Project of Guangxi

Natural Science Foundation of Guangxi Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

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