Titanium dioxide nanofibers induce angiogenic markers and genomic instability in lung cells leading to a highly dedifferentiated and fibrotic tumor formation in a xenograft model-Reference-Cited by-同舟云学术

Titanium dioxide nanofibers induce angiogenic markers and genomic instability in lung cells leading to a highly dedifferentiated and fibrotic tumor formation in a xenograft model

Published:2019 Issue:1 Volume:6 Page:286-304
ISSN:2051-8153
Container-title:Environmental Science: Nano
language:en
Short-container-title:Environ. Sci.: Nano

Author:

Medina-Reyes Estefany I.¹²³⁴⁵^ORCID,Delgado-Buenrostro Norma L.¹²³⁴⁵^ORCID,Déciga-Alcaraz Alejandro¹²³⁴⁵^ORCID,Freyre-Fonseca Verónica¹²³⁴⁵^ORCID,Flores-Flores José O.⁶³⁷⁸⁹,Hernández-Pando Rogelio¹⁰¹¹⁹⁵,Barrios-Payán Jorge¹⁰¹¹⁹⁵,Carrero Julio C.¹²¹³³⁸¹⁴,Sánchez-Pérez Yesennia¹⁵¹⁶¹⁷⁵^ORCID,García-Cuéllar Claudia M.¹⁵¹⁶¹⁷⁵^ORCID,Vaca-Paniagua Felipe¹²³⁴⁵^ORCID,Chirino Yolanda I.¹²³⁴⁵^ORCID

Affiliation:

1. Laboratorio de Carcinogénesis y Toxicología

2. Unidad de Biomedicina, Facultad de Estudios Superiores

3. Universidad Nacional Autónoma de México

4. Tlalnepantla

5. Mexico

6. Instituto de Ciencias Aplicadas y Tecnología

7. Circuito Exterior S/N

8. Ciudad Universitaria

9. Ciudad de México

10. Sección de Patología Experimental

11. Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán

12. Departamento de Inmunología

13. Instituto de Investigaciones Biomédicas

14. CP 04510 Ciudad de México

15. Subdirección de Investigación Básica

16. Instituto Nacional de Cancerología

17. CP 14080 Ciudad de México

Abstract

Lung adenocarcinoma cells exposed to TiO₂nanofibers enhanced tumor characteristics including angiogenic markers and genomic instability, and these cells can even acquire a more aggressive phenotype when grown in a xenograft nude mouse model.

Funder

Consejo Nacional de Ciencia y Tecnología

Publisher

Royal Society of Chemistry (RSC)

Subject

General Environmental Science,Materials Science (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2019/EN/C8EN01078A

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4. Hierarchically mesostructured porous TiO 2 hollow nanofibers for high performance glucose biosensing

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