Et3SiH + KOtBu provide multiple reactive intermediates that compete in the reactions and rearrangements of benzylnitriles and indolenines
Author:
Affiliation:
1. Department of Pure and Applied Chemistry
2. Glasgow
3. UK
4. GlaxoSmithKline Medicines Research Centre
5. Stevenage
Abstract
The combination of potassium tert-butoxide and triethylsilane provides simultaneous access to multiple reactive intermediates, radicals, H-atom donors, hydride donors and electron donors, giving scope for unprecedented reaction outcomes.
Funder
Engineering and Physical Sciences Research Council
GlaxoSmithKline
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2020/SC/D0SC04244G
Reference35 articles.
1. Lewis-base silane activation: from reductive cleavage of aryl ethers to selective ortho-silylation
2. Silylation of C–H bonds in aromatic heterocycles by an Earth-abundant metal catalyst
3. Catalytic C–H bond silylation of aromatic heterocycles
4. Potassium tert-Butoxide-Catalyzed Dehydrogenative C–H Silylation of Heteroaromatics: A Combined Experimental and Computational Mechanistic Study
5. Ionic and Neutral Mechanisms for C–H Bond Silylation of Aromatic Heterocycles Catalyzed by Potassium tert-Butoxide
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