Investigations on recyclisation and hydrolysis in avibactam mediated serine β-lactamase inhibition
Author:
Affiliation:
1. Department of Bioscience and Biotechnology
2. Sejong University
3. Seoul 143-747
4. Korea
5. Chemical Research Laboratory
6. University of Oxford
7. Oxford OX1 3TA
8. UK
Abstract
In contrast to the β-lactams, which react irreversibly, avibactam reacts reversibly with serine β-lactamases.
Funder
Medical Research Council
Engineering and Physical Sciences Research Council
AstraZeneca
Publisher
Royal Society of Chemistry (RSC)
Subject
Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2016/OB/C6OB00353B
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