10th anniversary of discovering cGAMP: synthesis and beyond-Reference-Cited by-同舟云学术

10th anniversary of discovering cGAMP: synthesis and beyond

Published:2023 Issue:4 Volume:10 Page:1086-1098
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Chen Chuo¹^ORCID

Affiliation:

1. Department of Biochemistry, UT Southwestern Medical Center, 5323 Harry Hines Boulevard, Dallas, TX 75390-9038, USA

Abstract

This article describes how the synergy between chemistry and biology facilitated the development of cyclic dinucleotides as a potential new treatment for cancer.

Funder

Cancer Prevention and Research Institute of Texas

National Cancer Institute

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/QO/D2QO02033E

Reference147 articles.

1. Intrinsic antiviral immunity

2. STING is an endoplasmic reticulum adaptor that facilitates innate immune signalling

3. The Adaptor Protein MITA Links Virus-Sensing Receptors to IRF3 Transcription Factor Activation

4. ERIS, an endoplasmic reticulum IFN stimulator, activates innate immune signaling through dimerization

5. MPYS Is Required for IFN Response Factor 3 Activation and Type I IFN Production in the Response of Cultured Phagocytes to Bacterial Second Messengers Cyclic-di-AMP and Cyclic-di-GMP

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1. Profiling of cyclic di‐adenyl and ‐guanyl nucleotides and their precursors and degradation products in bacteria using LC–MS/MS;SEPARATION SCIENCE PLUS;2024-02-22

2. Orthogonal Hydroxyl Functionalization of cGAMP Confers Metabolic Stability and Enables Antibody Conjugation;ACS Central Science;2023-11-15

3. One‐Flask Synthesis of Cyclic Diguanosine Monophosphate (c‐di‐GMP);Current Protocols;2023-04