Orthogonal Hydroxyl Functionalization of cGAMP Confers Metabolic Stability and Enables Antibody Conjugation-Reference-Cited by-同舟云学术

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Orthogonal Hydroxyl Functionalization of cGAMP Confers Metabolic Stability and Enables Antibody Conjugation

Published:2023-11-15 Issue:12 Volume:9 Page:2298-2305
ISSN:2374-7943
Container-title:ACS Central Science
language:en
Short-container-title:ACS Cent. Sci.

Author:

Lu Yong^ORCID,You Lin,Li Liping,Kilgore Jessica A.,Liu Shun,Wang Xiaoyu,Dai Yuanwei,Wei Qi,Shi Heping,Han Lei,Sun Lijun,Chen Zhijian J.,Zhang Xuewu,Williams Noelle S.,Chen Chuo^ORCID

Funder

National Cancer Institute

Welch Foundation

University of Texas Southwestern Medical Center

Cancer Prevention and Research Institute of Texas

National Institute of General Medical Sciences

Publisher

American Chemical Society (ACS)

Subject

General Chemical Engineering,General Chemistry

Link

https://pubs.acs.org/doi/pdf/10.1021/acscentsci.3c01122

Reference66 articles.

1. Cyclic GMP-AMP Is an Endogenous Second Messenger in Innate Immune Signaling by Cytosolic DNA

2. Cyclic GMP-AMP Containing Mixed Phosphodiester Linkages Is An Endogenous High-Affinity Ligand for STING

3. 10th anniversary of discovering cGAMP: synthesis and beyond

4. Cyclic GMP-AMP Synthase Is a Cytosolic DNA Sensor That Activates the Type I Interferon Pathway

5. Structures and Mechanisms in the cGAS-STING Innate Immunity Pathway

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