Studies of copper trafficking in a mouse model of Alzheimer's disease by positron emission tomography: comparison of64Cu acetate and64CuGTSM-Reference-Cited by-同舟云学术

Studies of copper trafficking in a mouse model of Alzheimer's disease by positron emission tomography: comparison of64Cu acetate and64CuGTSM

Published:2017 Issue:11 Volume:9 Page:1622-1633
ISSN:1756-5901
Container-title:Metallomics
language:en
Short-container-title:Metallomics

Author:

Andreozzi Erica M.¹²³⁴⁵,Torres Julia Baguña¹²³⁴⁵,Sunassee Kavitha¹²³⁴⁵,Dunn Joel¹²³⁴⁵,Walker-Samuel Simon⁶⁷⁴⁵^ORCID,Szanda Istvan¹²³⁴⁵,Blower Philip J.¹²³⁴⁵^ORCID

Affiliation:

1. Division of Imaging Sciences

2. Kings College London

3. St. Thomas Hospital

4. London

5. UK

6. UCL Centre for Advanced Biomedical Imaging

7. Division of Medicine

Abstract

Positron emission tomography with⁶⁴Cu demonstrates regionally selective delivery of copper to brain, which although modified in an Alzheimer's model, does not correlate with the location of amyloid plaques.

Funder

Medical Research Council

Engineering and Physical Sciences Research Council

Department of Health

Wellcome Trust

Alzheimer Society

National Institute for Health Research

Whitaker International Program

Cancer Research UK

Publisher

Oxford University Press (OUP)

Subject