Selective delivery of remarkably high levels of gadolinium to tumour cells using an arsonium salt-Reference-Cited by-同舟云学术

Selective delivery of remarkably high levels of gadolinium to tumour cells using an arsonium salt

Published:2021 Issue:70 Volume:57 Page:8806-8809
ISSN:1359-7345
Container-title:Chemical Communications
language:en
Short-container-title:Chem. Commun.

Author:

Windsor Madeline S. A.¹,Busse Madleen¹,Morrison Daniel E.¹,Baker Robert W.¹^ORCID,Hill Leila R.¹^ORCID,Rendina Louis M.¹²^ORCID

Affiliation:

1. School of Chemistry, The University of Sydney, Sydney, NSW 2006, Australia

2. The University of Sydney Nano Institute, Sydney, NSW 2006, Australia

Abstract

A triphenylarsonium targeting vector is far superior to the well-established, isosteric phosphonium analogue for tumour cell delivery of Gd3+.

Funder

Australian Research Council

Publisher

Royal Society of Chemistry (RSC)

Subject

Materials Chemistry,Metals and Alloys,Surfaces, Coatings and Films,General Chemistry,Ceramics and Composites,Electronic, Optical and Magnetic Materials,Catalysis

Link

http://pubs.rsc.org/en/content/articlepdf/2021/CC/D1CC03082E

Reference48 articles.

1. Mitochondria-Targeted Triphenylphosphonium-Based Compounds: Syntheses, Mechanisms of Action, and Therapeutic and Diagnostic Applications

2. Mitochondrial and plasma membrane potentials cause unusual accumulation and retention of rhodamine 123 by human breast adenocarcinoma-derived MCF-7 cells.

3. Monitoring of relative mitochondrial membrane potential in living cells by fluorescence microscopy.

4. Rhodamine 123 as a probe of transmembrane potential in isolated rat-liver mitochondria: spectral and metabolic properties

5. Quantitative assay by flow cytometry of the mitochondrial membrane potential in intact cells

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