A high-spin alkylperoxo–iron(<scp>iii</scp>) complex with <i>cis</i>-anionic ligands: implications for the superoxide reductase mechanism-Reference-Cited by-同舟云学术

A high-spin alkylperoxo–iron(iii) complex with cis-anionic ligands: implications for the superoxide reductase mechanism

Published:2024 Issue:2 Volume:15 Page:528-533
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Devi Tarali¹²^ORCID,Dutta Kuheli¹,Deutscher Jennifer¹^ORCID,Mebs Stefan³^ORCID,Kuhlmann Uwe⁴,Haumann Michael³,Cula Beatrice¹,Dau Holger³^ORCID,Hildebrandt Peter⁴^ORCID,Ray Kallol¹^ORCID

Affiliation:

1. Institut für Chemie, Humboldt-Universitat zu Berlin, Brook-Taylor-Straße 2, 12489 Berlin, Germany

2. Department of Inorganic and Physical Chemistry, Indian Institute of Science, Bangalore, Karnataka-560012, India

3. Department of Physics, Freie Universität Berlin, Arnimallee 14, 14195 Berlin, Germany

4. Institut für Chemie, Technische Universität Berlin, Fakultät II, Straße des 17. Juni 135, 10623 Berlin, Germany

Abstract

Cis-anionic ligands stabilize high-spin Fe(iii)–alkylperoxo complexes against homolytic O–O bond cleavage to form an iron(iv)–oxo moiety. The study provides some basis to speculate the structure of peroxy intermediates in superoxide reductase.

Funder

Einstein Stiftung Berlin

Bundesministerium für Bildung und Forschung

Alexander von Humboldt-Stiftung

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2024/SC/D3SC05603A

Reference37 articles.

1. Dioxygen Activation by Enzymes with Mononuclear Non-Heme Iron Active Sites

2. Structure and Chemistry of Cytochrome P450

3. Cytochrome P450 Compound I: Capture, Characterization, and C-H Bond Activation Kinetics

4. P450 Enzymes: Their Structure, Reactivity, and Selectivity—Modeled by QM/MM Calculations

5. Finding Intermediates in the O2 Activation Pathways of Non-Heme Iron Oxygenases