An antibiotic concentration gradient microfluidic device integrating surface-enhanced Raman spectroscopy for multiplex antimicrobial susceptibility testing-Reference-Cited by-同舟云学术

An antibiotic concentration gradient microfluidic device integrating surface-enhanced Raman spectroscopy for multiplex antimicrobial susceptibility testing

Published:2022 Issue:9 Volume:22 Page:1805-1814
ISSN:1473-0197
Container-title:Lab on a Chip
language:en
Short-container-title:Lab Chip

Author:

Lin Shang-Jyun¹,Chao Po-Hsuan¹,Cheng Ho-Wen²³,Wang Juen-Kai²⁴⁵,Wang Yuh-Lin⁴^ORCID,Han Yin-Yi⁶⁷,Huang Nien-Tsu¹⁸^ORCID

Affiliation:

1. Graduate Institute of Biomedical Electronics and Bioinformatics, National Taiwan University, Taipei, Taiwan

2. Institute of Atomic and Molecular Sciences, Academia Sinica, Taipei, Taiwan

3. International Graduate Program of Molecular Science and Technology, National Taiwan University (NTU-MST) and Taiwan International Graduate Program (TIGP), Academia Sinica, Taipei, Taiwan

4. Center for Condensed Matter Sciences, National Taiwan University, Taipei, Taiwan

5. Center for Atomic Initiative for New Materials, National Taiwan University, Taipei, Taiwan

6. Department of Anesthesiology, National Taiwan University Hospital, Taipei, Taiwan

7. Department of Trauma, National Taiwan University Hospital, Taipei, Taiwan

8. Department of Electrical Engineering, National Taiwan University, Taipei, Taiwan

Abstract

We developed a microfluidic device to generate the concentration gradient of antibiotics along a series of lateral microwells to encapsulate bacteria and perform in situ multiplex surface-enhanced Raman scattering (SERS)-AST.

Funder

Ministry of Science and Technology, Taiwan

Publisher

Royal Society of Chemistry (RSC)

Subject

Biomedical Engineering,General Chemistry,Biochemistry,Bioengineering

Link

http://pubs.rsc.org/en/content/articlepdf/2022/LC/D2LC00012A

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