Assessment of the rules related to gaining activity against Gram-negative bacteria-Reference-Cited by-同舟云学术

Assessment of the rules related to gaining activity against Gram-negative bacteria

Published:2021 Issue:4 Volume:12 Page:593-601
ISSN:2632-8682
Container-title:RSC Medicinal Chemistry
language:en
Short-container-title:RSC Med. Chem.

Author:

Ropponen Henni-Karoliina¹²³⁴⁵^ORCID,Diamanti Eleonora¹²³,Siemens Alexandra⁶⁷⁸³,Illarionov Boris⁶⁷⁸³,Haupenthal Jörg¹²³^ORCID,Fischer Markus⁶⁷⁸³^ORCID,Rottmann Matthias⁹¹⁰¹¹¹²¹³^ORCID,Witschel Matthias¹⁴¹⁵³,Hirsch Anna K. H.¹²³⁴⁵^ORCID

Affiliation:

1. Helmholtz Institute for Pharmaceutical Research Saarland (HIPS) – Helmholtz Centre for Infection Research (HZI)

2. 66123 Saarbrücken

3. Germany

4. Department of Pharmacy

5. Saarland University

6. Hamburg School of Food Science

7. University of Hamburg

8. 20146 Hamburg

9. Swiss Tropical and Public Health Institute

10. 4002 Basel

11. Switzerland

12. Universität Basel

13. 4003 Basel

14. BASF-SE

15. 67056 Ludwigshafen

Abstract

Evaluation of the applicability of Gram-negative activity rules using 16 amino acid modified compounds against a panel of Escherichia coli and its mutant strains.

Funder

Helmholtz Association

Verband der Chemischen Industrie

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Pharmaceutical Science,Pharmacology,Molecular Medicine,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/MD/D0MD00409J

Reference42 articles.

1. Analysis of the clinical antibacterial and antituberculosis pipeline

2. Mastering the Gram-negative bacterial barrier – Chemical approaches to increase bacterial bioavailability of antibiotics