Strychnine and its mono- and dimeric analogues: a pharmaco-chemical perspective-Reference-Cited by-同舟云学术

Strychnine and its mono- and dimeric analogues: a pharmaco-chemical perspective

Published:2022 Issue:10 Volume:39 Page:1910-1937
ISSN:0265-0568
Container-title:Natural Product Reports
language:en
Short-container-title:Nat. Prod. Rep.

Author:

Zlotos Darius P.¹^ORCID,Mandour Yasmine M.²^ORCID,Jensen Anders A.³^ORCID

Affiliation:

1. Department of Pharmaceutical Chemistry, Faculty of Pharmacy and Biotechnology, The German University in Cairo, New Cairo City, 11835 Cairo, Egypt

2. School of Life and Medical Sciences, University of Hertfordshire hosted by Global Academic Foundation, New Administrative Capital, Cairo, Egypt

3. Department of Drug Design and Pharmacology, Faculty of Health and Medical Sciences, University of Copenhagen, DK-2100 Copenhagen, Denmark

Abstract

Since its isolation in 1818, strychnine has attracted the attention of chemists and pharmacologists. Here, we discuss structures, syntheses, metabolic transformations, and pharmacological actions of the alkaloid and its mono- and dimeric analogues.

Funder

Deutscher Akademischer Austauschdienst

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Drug Discovery,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2022/NP/D1NP00079A

Reference209 articles.

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2. Die tödliche Brechnuss. Strychnin - von der Isolierung zur Totalsynthese

3. J.Buckingham , Bitter Nemesis. The Intimate History of Strychnine , CRC Press , Boca Raton, USA, FL , 2008

4. General Medical Council of Great Britain , British Pharmacopeia , Spottiswoode & Co. , London , 1867 , p. 218 , https://archive.org/details/britishpharmacop00gene

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