Oxidant- and metal-free synthesis of 4(3H)-quinazolinones from 2-amino-N-methoxybenzamides and aldehydes via acid-promoted cyclocondensation and elimination-Reference-Cited by-同舟云学术

Oxidant- and metal-free synthesis of 4(3H)-quinazolinones from 2-amino-N-methoxybenzamides and aldehydes via acid-promoted cyclocondensation and elimination

Published:2014 Issue:50 Volume:4 Page:26434-26438
ISSN:2046-2069
Container-title:RSC Adv.
language:en
Short-container-title:RSC Adv.

Author:

Cheng Ran¹²³⁴,Tang Linlin¹²³⁴,Guo Tianjian¹²³⁴,Zhang-Negrerie Daisy¹²³⁴,Du Yunfei¹²³⁴⁵,Zhao Kang¹²³⁴

Affiliation:

1. Tianjin Key Laboratory for Modern Drug Delivery & High-Efficiency

2. School of Pharmaceutical Science and Technology

3. Tianjin University

4. Tianjin 300072, China

5. Collaborative Innovation Center of Chemical Science and Engineering (Tianjin)

Abstract

This paper presents a novel one-pot synthesis of biologically relevant 4(3H)-quinazolinones, in the absence of oxidants or heavy-metal catalysts.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2014/RA/C4RA04331F

Reference72 articles.

1. Novel Nonpeptide CCK-B Antagonists: Design and Development of Quinazolinone Derivatives as Potent, Selective, and Orally Active CCK-B Antagonists

2. Privileged structure-based quinazolinone natural product-templated libraries: Identification of novel tubulin polymerization inhibitors

3. The chemistry of recently isolated naturally occurring quinazolinone alkaloids

4. Design and Synthesis of a Quinazolinone Natural Product-Templated Library with Cytotoxic Activity

5. N-Hydroxypyridones, Phenylhydrazones, and a Quinazolinone from Isaria farinosa

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