Novel Nonpeptide CCK-B Antagonists: Design and Development of Quinazolinone Derivatives as Potent, Selective, and Orally Active CCK-B Antagonists-Reference-Cited by-同舟云学术

Novel Nonpeptide CCK-B Antagonists: Design and Development of Quinazolinone Derivatives as Potent, Selective, and Orally Active CCK-B Antagonists

Published:1998-03-01 Issue:7 Volume:41 Page:1042-1049
ISSN:0022-2623
Container-title:Journal of Medicinal Chemistry
language:en
Short-container-title:J. Med. Chem.

Author:

Padia Janak K.¹,Field Mark¹,Hinton Joanna¹,Meecham Ken¹,Pablo Julius¹,Pinnock Rob¹,Roth Bruce D.¹,Singh Lakhbir¹,Suman-Chauhan Nirmala¹,Trivedi Bharat K.¹,Webdale Louise¹

Affiliation:

1. Departments of Chemistry and of Pharmacokinetics and Drug Metabolism, Parke-Davis Pharmaceutical Research, Division of Warner-Lambert Company, 2800 Plymouth Road, Ann Arbor, Michigan 48105, and Parke-Davis Neuroscience Research Centre, Cambridge University Fotvie Site, Robinson Way, Cambridge CB2 2QB, U.K.

Publisher

American Chemical Society (ACS)

Subject

Drug Discovery,Molecular Medicine

Link

https://pubs.acs.org/doi/pdf/10.1021/jm970373j

Reference33 articles.

1. (a) Preliminary accounts of this work were presented at the 211th National ACS Meeting in New Orleans, LA, 1996.

2. (b) Padia, J. K. Novel heterocycles as cholecystokinin (CCK) ligands. International Patent Application No. WO 96/20178.

3. Localization and molecular heterogeneity of cholecystokinin in the central and peripheral nervous system

4. Distinct cholecystokinin receptors in brain and pancreas.

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