Fucoxanthin alleviated myocardial ischemia and reperfusion injury through inhibition of ferroptosis <i>via</i> the NRF2 signaling pathway-Reference-Cited by-同舟云学术

Fucoxanthin alleviated myocardial ischemia and reperfusion injury through inhibition of ferroptosis via the NRF2 signaling pathway

Published:2023 Issue:22 Volume:14 Page:10052-10068
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Yan Jing¹²³,Li Zehua¹²³,Liang Yu¹²³,Yang Chaobo¹²³,Ou Wen¹²³,Mo Huaqiang⁴,Tang Min¹²³,Chen Deshu¹²³,Zhong Chongbin¹²³,Que Dongdong¹²³,Feng Liyun¹²³,Xiao Hua¹²³,Song Xudong¹²³,Yang Pingzhen¹²³^ORCID

Affiliation:

1. Department of Cardiology, Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong, China

2. Laboratory of Heart Center, Zhujiang Hospital, Southern Medical University, Guangdong, China

3. Guangdong Provincial Key Laboratory of Shock and Microcirculation, Southern Medical University, Guangdong, China

4. Department of Cardiology, Shenzhen People's Hospital, the Second Affiliated Hospital, Jinan University, Guangdong, China

Abstract

FX stimulated NRF2 to ameliorate mitochondrial dysfunction and inhibit overloading ROS and Fe2+, which contribute to lipid peroxidation and thus lead to ferroptosis, alleviating MIRI.

Funder

National Natural Science Foundation of China

Basic and Applied Basic Research Foundation of Guangdong Province

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2023/FO/D3FO02633G

Reference59 articles.

1. Percutaneous Mechanical Circulatory Support Versus Intra-Aortic Balloon Pump in Cardiogenic Shock After Acute Myocardial Infarction

2. Multimodality imaging in ischaemic heart failure