Evaluation of the anti-osteoporotic effect of a low-phenylalanine whey protein hydrolysate in an ovariectomized mice model-Reference-Cited by-同舟云学术

Evaluation of the anti-osteoporotic effect of a low-phenylalanine whey protein hydrolysate in an ovariectomized mice model

Published:2022 Issue:7 Volume:13 Page:3957-3967
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Bu Tingting¹^ORCID,Zhang Ling¹,Liu Ling²,Yu Songfeng²^ORCID,Zheng Jiexia²,Wu Jianping³^ORCID,Yang Kai¹

Affiliation:

1. Department of Food Science and Technology, Zhejiang University of Technology, Hangzhou, 310014, China

2. College of Biosystems Engineering and Food Science, Zhejiang University, Hangzhou, 310058, China

3. Department of Agricultural, Food and Nutritional Science, University of Alberta, Edmonton, Alberta, T6G 2P5, Canada

Abstract

A low-Phe containing whey hydrolysate (LPH) and its original whey protein hydrolysate (TAH) exerted an anti-osteoporotic effect on ovariectomized mice through dual-regulation of bone remodeling.

Funder

National Key Research and Development Program of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D1FO04030H

Reference58 articles.

1. Phenylalanine hydroxylase deficiency: diagnosis and management guideline

2. The Maternal Phenylketonuria International Study: 1984–2002

3. Phenylketonuria: nutritional advances and challenges

4. Suboptimal outcomes in patients with PKU treated early with diet alone: Revisiting the evidence

5. Bone Status in Patients with Phenylketonuria: A Systematic Review

Cited by 5 articles. 订阅此论文施引文献订阅此论文施引文献，注册后可以免费订阅5篇论文的施引文献，订阅后可以查看论文全部施引文献

1. Phenylalanine deprivation inhibits multiple myeloma progression by perturbing endoplasmic reticulum homeostasis;Acta Pharmaceutica Sinica B;2024-08

2. Positive effects of extracellular polysaccharides from Paecilomyces hepiali on immune-enhancing properties by regulating gut microbiota in cyclophosphamide-induced mice;International Journal of Biological Macromolecules;2024-08

3. Immunomodulatory activity and mechanism of Chinese yam polysaccharide after sulfated modification;Industrial Crops and Products;2023-07

4. Whey Protein Hydrolysate Ameliorated High-Fat-Diet Induced Bone Loss via Suppressing Oxidative Stress and Regulating GSK-3β/Nrf2 Signaling Pathway;Nutrients;2023-06-24

5. A Low-Phenylalanine-Containing Whey Protein Hydrolysate Stimulates Osteogenic Activity through the Activation of p38/Runx2 Signaling in Osteoblast Cells;Nutrients;2022-07-29