Targeting proteases involved in the viral replication of SARS-CoV-2 by sesquiterpene lactones from chicory (<i>Cichorium intybus</i> L.)-Reference-Cited by-同舟云学术

Targeting proteases involved in the viral replication of SARS-CoV-2 by sesquiterpene lactones from chicory (Cichorium intybus L.)

Published:2022 Issue:17 Volume:13 Page:8977-8988
ISSN:2042-6496
Container-title:Food & Function
language:en
Short-container-title:Food Funct.

Author:

Ávila-Gálvez María Ángeles¹²^ORCID,Rafael-Pita Carlos¹²,Fernández Naiara¹,Baixinho João¹³,Anastácio José D.¹²,Cankar Katarina⁴^ORCID,Bosch Dirk⁴,Nunes dos Santos Cláudia¹²

Affiliation:

1. Instituto de Biologia Experimental e Tecnológica (iBET), Av. República, Qta. Marquês, 2780-157 Oeiras, Portugal

2. NOVA Medical School|Faculdade de Ciências Médicas, NMS|FCM, Universidade Nova de Lisboa, Lisboa, Portugal

3. Instituto de Tecnologia Química e Biológica António Xavier, Universidade Nova de Lisboa, Av. da República, 2780-157 Oeiras, Portugal

4. Wageningen University and Research, Wageningen Plant Research, BU Bioscience, Droevendaalsesteeg 1, 6708PB Wageningen, The Netherlands

Abstract

Sesquiterpene lactones (STLs) from chicory root extract may inhibit SARS-CoV-2 Mpro and PLpro.

Funder

Horizon 2020 Framework Programme

Publisher

Royal Society of Chemistry (RSC)

Subject

General Medicine,Food Science

Link

http://pubs.rsc.org/en/content/articlepdf/2022/FO/D2FO00933A

Reference71 articles.

1. Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) and coronavirus disease-2019 (COVID-19): The epidemic and the challenges

2. Post-COVID-19 Symptom Burden: What is Long-COVID and How Should We Manage It?

3. The COVID-19 pandemic and its potential enduring impact on children

4. The Molecular Biology of Coronaviruses

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