Fullerene nanoparticles: a promising candidate for the alleviation of silicosis-associated pulmonary inflammation
Author:
Affiliation:
1. Beijing National Laboratory for Molecular Sciences
2. Key Laboratory of Molecular Nanostructure and Nanotechnology
3. CAS Research/Education Center for Excellence in Molecular Sciences
4. Institute of Chemistry
5. Chinese Academy of Sciences
Abstract
Pulmonary administration of FNs alleviates silicosis-associated pulmonary inflammation by inhibiting crystalline silica-induced ROS and the activation of NLRP3 inflammasome.
Funder
National Natural Science Foundation of China
Publisher
Royal Society of Chemistry (RSC)
Subject
General Materials Science
Link
http://pubs.rsc.org/en/content/articlepdf/2020/NR/D0NR04401F
Reference51 articles.
1. STING-dependent sensing of self-DNA drives silica-induced lung inflammation
2. Silicosis
3. The NLRP3 inflammasome in pathogenic particle and fibre-associated lung inflammation and diseases
4. Prevention of crystalline silica-induced inflammation by the anti-malarial hydroxychloroquine
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