G-quadruplex DNA and ligand interaction in living cells using NMR spectroscopy
Author:
Affiliation:
1. Univ. Bordeaux
2. ARNA Laboratory
3. F-33000 Bordeaux
4. France
5. INSERM
6. CNRS
7. Microbiologie Fondamentale et Pathogénicité
Abstract
Using in-cell NMR spectroscopy to probe ligand binding to a G-quadruplex nucleic acid.
Funder
Agence Nationale de la Recherche
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2015/SC/C4SC03853C
Reference43 articles.
1. Drugging Topoisomerases: Lessons and Challenges
2. The application of DNA and RNA G-quadruplexes to therapeutic medicines
3. G-quadruplexes as targets for drug design
4. Targeting G-quadruplexes in gene promoters: a novel anticancer strategy?
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