The food additive E171 and titanium dioxide nanoparticles indirectly alter the homeostasis of human intestinal epithelial cells in vitro-Reference-Cited by-同舟云学术

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The food additive E171 and titanium dioxide nanoparticles indirectly alter the homeostasis of human intestinal epithelial cells in vitro

Published:2019 Issue:5 Volume:6 Page:1549-1561
ISSN:2051-8153
Container-title:Environmental Science: Nano
language:en
Short-container-title:Environ. Sci.: Nano

Author:

Dorier Marie¹²³⁴⁵,Béal David¹²³⁴⁵,Tisseyre Céline¹²³⁴⁵,Marie-Desvergne Caroline⁶⁷⁸⁹¹⁰,Dubosson Muriel⁶⁷⁸⁹¹⁰,Barreau Frédérick¹¹¹²¹³¹⁴¹⁵,Houdeau Eric¹⁶¹⁷¹⁸¹⁹²⁰,Herlin-Boime Nathalie²¹⁷²²²³²⁴,Rabilloud Thierry²⁵²⁶²⁷²⁸²⁹^ORCID,Carriere Marie¹²³⁴⁵^ORCID

Affiliation:

1. Univ. Grenoble-Alpes

2. INAC

3. SyMMES

4. Chimie Interface Biologie pour l'Environnement, la Santé et la Toxicologie (CIBEST)

5. F-38000 Grenoble

6. Université Grenoble-Alpes

7. CEA

8. Nanosafety Platform

9. Medical Biology Laboratory (LBM)

10. F-38054 Grenoble

11. INSERM

12. UMR 1220

13. Institut de Recherche en Santé Digestive

14. Toulouse

15. France

16. Toxalim (Research Centre in Food Toxicology)

17. Université de Toulouse

18. INRA

19. ENVT

20. INP-Purpan

21. NIMBE

22. CNRS

23. Université Paris-Saclay

24. CEA Saclay

25. ProMD

26. UMR CNRS 5249

27. CEA Grenoble

28. DRF/BIG/CBM

29. Laboratory of Chemistry and Biology of Metals

Abstract

Repeated exposure to E171 or TiO₂-NPs, in vitro, induce moderate inflammation and mucus secretion in intestinal cells.

Funder

Agence Nationale de la Recherche

Agence de l'Environnement et de la Maîtrise de l'Energie

Commissariat à l'Énergie Atomique et aux Énergies Alternatives

Agence Nationale de Sécurité Sanitaire de l’Alimentation, de l’Environnement et du Travail

Publisher

Royal Society of Chemistry (RSC)

Subject

General Environmental Science,Materials Science (miscellaneous)

Link

http://pubs.rsc.org/en/content/articlepdf/2019/EN/C8EN01188E

Reference65 articles.

1. Titanium dioxide nanoparticles: a review of current toxicological data

2. European Commission , Recommendation on the definition of a nanomaterial, Official Journal of the European Union , 2011 , 2011/696/EU

3. Food grade titanium dioxide disrupts intestinal brush border microvilli in vitro independent of sedimentation

4. Titanium Dioxide Nanoparticles in Food and Personal Care Products

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