Identification of hepatocellular carcinoma and paracancerous tissue based on the peak area in FTIR microspectroscopy

Author:

Peng Wenyu1ORCID,Yin Junkai1,Ma Jing1,Zhou Xiaojie2,Chang Chao1

Affiliation:

1. Innovation Laboratory of Terahertz Biophysics, National Innovation Institute of Defense Technology, Beijing 100071, China

2. National Facility for Protein Science in Shanghai, Shanghai Advanced Research Institute, Chinese Academy of Science, Shanghai 201210, China

Abstract

This study demonstrates that nonlinear SVM model combined with the features of peak area performs well in the identification of HCC foci and paracancerous tissue, and also proves that the performance is better than full spectrum-based feature.

Funder

National Natural Science Foundation of China

Publisher

Royal Society of Chemistry (RSC)

Subject

General Engineering,General Chemical Engineering,Analytical Chemistry

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