Solvent-free and montmorillonite K10-catalyzed domino reactions for the synthesis of pyrazoles with alkynylester as a dual synthon

Author:

Annes Sesuraj Babiola12345ORCID,Saritha Rajendhiran12345,Subramanian Saravanan67895ORCID,Shankar Bhaskaran110115ORCID,Ramesh Subburethinam12345ORCID

Affiliation:

1. Department of Chemistry

2. School of Chemical and Biotechnology

3. SASTRA Deemed University

4. Thanjavur 613401

5. India

6. Inorganic Materials and Catalysis Division

7. Central Salt and Marine Chemicals Research Institute (CSMCRI)

8. Council of Scientific and Industrial Research (CSIR)

9. Bhavnagar 364 002

10. Sethu Institute of Technology

11. Kariapatti 626115

Abstract

A highly regioselective, solvent-free and montmorillonite K10 clay-catalyzed domino process with an unprecedented C–C bond formation reaction is described for the synthesis of new class of tri-substituted and di-substituted pyrazole derivatives.

Funder

Department of Science and Technology, Ministry of Science and Technology, India

Publisher

Royal Society of Chemistry (RSC)

Subject

Pollution,Environmental Chemistry

Reference41 articles.

1. J. Elguero , P.Goya , N.Jagerovic and A. M. S.Silva , in Pyrazoles as Drugs: Facts and Fantasies in Targets in Heterocyclic Systems , ed. O. A. Attanasi and D. Spinelli , Italian Society of Chemistry , Rome , 2001 , vol. 6 , pp. 52–98

2. J. Elguero , in Comprehensive Heterocyclic Chemistry , ed. A. R. Katritzky , C. W. Rees and E. F. V. Scriven , Pergamon Press , Oxford, UK , 1984 , 5 , 273–291

3. J. Elguero , in Comprehensive Heterocyclic Chemistry II , ed. I. Shinkai , Pergamon Press , Oxford, U.K. , 1996 , 3 , 1–75

4. Synthesis, spectral studies and tritiation of the cannabinoid antagonist SR141716A

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