Creating de novo peptide-based bioactivities: from assembly to origami

Author:

Ma Yuxing123,Li Xiaofang124,Zhao Ruoyang12,Wu Enqi3,Du Qiqige12,Guo Jun45,Wang Liping12,Zhang Feng1245ORCID

Affiliation:

1. Wenzhou Institute, University of Chinese Academy of Sciences, Wenzhou 325001, China

2. Oujiang Laboratory, Wenzhou, Zhejiang 325000, P. R. China

3. Inner Mongolia Key Laboratory of Tick-Borne Zoonotic Infectious Disease, Department of Medicine, Hetao College, Bayannur, 015000, China

4. Key Laboratory of Optical Technology and Instrument for Medicine, Ministry of Education, University of Shanghai for Science and Technology, Shanghai, 200093, P. R. China

5. State Key Laboratory of Respiratory Disease, Guangzhou Institute of Oral Disease, Stomatology Hospital, School of Biomedical Engineering, Guangzhou Medical University, Guangzhou 511436, China

Abstract

Chain-like peptides and DNA share obvious similarities in terms of chain hybridization; thus, replacing DNA with peptides to create bioactivities not only has high theoretical feasibility but also provides a new bottom-up synthetic strategy.

Funder

National Natural Science Foundation of China

National Key Research and Development Program of China

Wenzhou Institute of Biomaterials and Engineering

Research Program of Science and Technology at Universities of Inner Mongolia Autonomous Region

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Cited by 1 articles. 订阅此论文施引文献 订阅此论文施引文献,注册后可以免费订阅5篇论文的施引文献,订阅后可以查看论文全部施引文献

1. Messenger RNA-Based Therapeutics and Vaccines: What’s beyond COVID-19?;ACS Pharmacology & Translational Science;2023-07-03

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