Genistein and daidzein decrease food intake and body weight gain in mice, and alter LXR signaling in vivo and in vitro
Author:
Affiliation:
1. Food Science and Technology
2. Oregon State University
3. Corvallis
4. USA
5. Human Nutrition Program
6. Ohio State University
7. Columbus
8. Food Science and Engineering
9. Northeast Forestry University
10. Harbin
11. China
Abstract
Genistein and daidzein decrease mice food intake, ameliorate symptoms of metabolic syndrome, including decreasing body weight gain, and improving glucose metabolism, and appear to produce differential effects, possibly via the regulation of LXR-mediated pathways.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Medicine,Food Science
Link
http://pubs.rsc.org/en/content/articlepdf/2018/FO/C8FO01718B
Reference34 articles.
1. Gene Expression Patterns Are Altered in Athymic Mice and Metabolic Syndrome Factors Are Reduced in C57BL/6J Mice Fed High-Fat Diets Supplemented with Soy Isoflavones
2. Genistein Decreases Food Intake, Body Weight, and Fat Pad Weight and Causes Adipose Tissue Apoptosis in Ovariectomized Female Mice
3. Molecular mechanisms of action of the soy isoflavones includes activation of promiscuous nuclear receptors. A review
4. Genistein and daidzein repress adipogenic differentiation of human adipose tissue-derived mesenchymal stem cells via Wnt/β-catenin signalling or lipolysis
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