Biocatalytic kinetic resolution of d,l-pantolactone by using a novel recombinant d-lactonase
Author:
Affiliation:
1. Brother Research Center
2. Jiangxi Brother Pharmaceutical Co.,Ltd
3. Jiujiang
4. China
Abstract
d-Pantolactone is a key chiral intermediate for the synthesis of d-pantothenic acid and its derivatives.
Publisher
Royal Society of Chemistry (RSC)
Subject
General Chemical Engineering,General Chemistry
Link
http://pubs.rsc.org/en/content/articlepdf/2021/RA/D0RA09053K
Reference18 articles.
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2. Cloning and overexpression of ketopantoic acid reductase gene from Stenotrophomonas maltophilia and its application to stereospecific production of d-pantoic acid
3. Asymmetric reduction of ketopantolactone using a strictly (R)-stereoselective carbonyl reductase through efficient NADPH regeneration and the substrate constant-feeding strategy
4. Chemoenzymatic Synthesis of Vitamin B5-Intermediate (R)-Pantolactone via Combined Asymmetric Organo- and Biocatalysis
5. l-Pantoyl lactone dehydrogenase from Rhodococcus erythropolis: genetic analyses and application to the stereospecific oxidation of l-pantoyl lactone
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