Visible-light-mediated direct synthesis of phosphorotrithioates as potent anti-inflammatory agents from white phosphorus-Reference-Cited by-同舟云学术

Visible-light-mediated direct synthesis of phosphorotrithioates as potent anti-inflammatory agents from white phosphorus

Published:2019 Issue:2 Volume:6 Page:190-194
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Lu Guozhang¹²³⁴⁵,Chen Jun⁶⁴⁵⁷,Huangfu Xinlei¹²³⁴⁵,Li Xueyan¹²³⁴⁵,Fang Meijuan⁶⁴⁵⁷^ORCID,Tang Guo¹²³⁴⁵^ORCID,Zhao Yufen¹²³⁴⁵^ORCID

Affiliation:

1. Department of Chemistry

2. College of Chemistry and Chemical Engineering

3. and the Key Laboratory for Chemical Biology of Fujian Province

4. Xiamen University

5. Xiamen

6. School of Pharmaceutical Sciences and the Key Laboratory of Innovative Drug Target Research

7. China

Abstract

The reaction of P₄ with arylthiols in the presence of Na₂–eosin Y under visible light gave phosphorotrithioites. Subsequent oxidation of phosphorotrithioites produced phosphorotrithioates. The phosphorotrithioate 3f presents good inflammation reducing characteristics.

Funder

National Natural Science Foundation of China

Natural Science Foundation of Fujian Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/QO/C8QO01087K

Reference61 articles.

1. The Chemistry of Organophosphorus Compounds , ed. F. H. Hartley , Wiley , New York , 1996

2. Phosphorus Chemistry II , in Topics in Current Chemistry , ed. L. Montchamp , Springer , Switzerland , 2015