Electrochemical synthesis of 1,2,4-oxadiazoles from amidoximes through dehydrogenative cyclization-Reference-Cited by-同舟云学术

Electrochemical synthesis of 1,2,4-oxadiazoles from amidoximes through dehydrogenative cyclization

Published:2021 Issue:48 Volume:19 Page:10611-10616
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Jiang Chan¹,Li Mingfang¹,Xu Leitao¹,Yi Yangjie¹,Ye Jiao¹^ORCID,Hu Aixi¹^ORCID

Affiliation:

1. College of Chemistry and Chemical Engineering, Hunan University, Changsha 410082, China

Abstract

The iminoxy radical generated through anodic oxidation from amidoximes undergoes 1,5-HAT and intramolecular cyclization to obtain 1,2,4-oxadiazoles in good to high yields.

Funder

Natural Science Foundation of Hunan Province

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2021/OB/D1OB02040D

Reference38 articles.

1. Recent Advances in the Chemistry of 1,2,4-OxadiazolesaaDedicated to Professor Nicolò Vivona on the occasion of his 75th birthday.

2. The new era of 1,2,4-oxadiazoles

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4. Drug synthesis methods and manufacturing technology

5. Three step, one-pot process to prepare thiophene-2-carbonyl chloride (TCC), a key raw material in the manufacture of tioxazafen (Nemastrike®)

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