TFA-Mediated Synthesis of 1,2,4-Oxadiazoles from Carbamates and Nitriles-Reference-Cited by-同舟云学术

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TFA-Mediated Synthesis of 1,2,4-Oxadiazoles from Carbamates and Nitriles

Published:2024-04-29 Issue:10 Volume:89 Page:7330-7338
ISSN:0022-3263
Container-title:The Journal of Organic Chemistry
language:en
Short-container-title:J. Org. Chem.

Author:

Zhuang Daijiao¹,Wu Yuankun¹,Wang Shuairan¹,Tao Yuelin¹,Liu Peihua²,Luo Xiaofeng³,Wang Tianqiang³,Yan Rulong¹^ORCID

Affiliation:

1. State Key Laboratory of Applied Organic Chemistry, College of Chemistry and Chemical Engineering, Lanzhou University, Lanzhou 730000, Gansu, China

2. Research Institute of Oil and Gas Technology of Changqing Oilfield Company, Xian 710018, Shanxi, China

3. Chengdu Guibao Science and Technology Company, Ltd., Chengdu 610041, Sichuan, China

Funder

National Natural Science Foundation of China

Natural Science Foundation of Gansu Province

Gansu Science and Technology Program

Sichuan Science and Technology Program

Publisher

American Chemical Society (ACS)

Link

https://pubs.acs.org/doi/pdf/10.1021/acs.joc.4c00640

Reference58 articles.

1. Bioisosterism: A Rational Approach in Drug Design

2. 2-Alkylamino- and alkoxy-substituted 2-amino-1,3,4-oxadiazoles—O-Alkyl benzohydroxamate esters replacements retain the desired inhibition and selectivity against MEK (MAP ERK kinase)

3. Discovery of amide and heteroaryl isosteres as carbamate replacements in a series of orally active γ-secretase inhibitors

4. Oxadiazoles in Medicinal Chemistry

5. Three step, one-pot process to prepare thiophene-2-carbonyl chloride (TCC), a key raw material in the manufacture of tioxazafen (Nemastrike®)

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