Synthesis of mucoadhesive thiol-bearing microgels from 2-(acetylthio)ethylacrylate and 2-hydroxyethylmethacrylate: novel drug delivery systems for chemotherapeutic agents to the bladder-Reference-Cited by-同舟云学术

Synthesis of mucoadhesive thiol-bearing microgels from 2-(acetylthio)ethylacrylate and 2-hydroxyethylmethacrylate: novel drug delivery systems for chemotherapeutic agents to the bladder

Published:2015 Issue:32 Volume:3 Page:6599-6604
ISSN:2050-750X
Container-title:Journal of Materials Chemistry B
language:en
Short-container-title:J. Mater. Chem. B

Author:

Cook M. T.¹²³⁴⁵,Schmidt S. A.⁶⁷⁸⁵,Lee E.⁶⁷⁸⁵,Samprasit W.⁹¹⁰¹¹¹²¹³,Opanasopit P.⁹¹⁰¹¹¹²¹³,Khutoryanskiy V. V.⁶⁷⁸⁵

Affiliation:

1. Department of Pharmacy

2. Life and Medical Sciences

3. University of Hertfordshire

4. Hatfield

5. UK

6. School of Pharmacy

7. University of Reading

8. Reading

9. Pharmaceutical Development of Green Innovations Group (PDGIG)

10. Faculty of Pharmacy

11. Silpakorn University

12. Nakhon Pathom

13. Thailand

Abstract

Thiol-bearing microgels have been synthesised from copolymerisation of 2-(acetylthio)ethylacrylate and 2-hydroxyethylmethacrylate, and subsequent deprotection using sodium thiomethoxide.

Publisher

Royal Society of Chemistry (RSC)

Subject

General Materials Science,Biomedical Engineering,General Chemistry,General Medicine

Link

http://pubs.rsc.org/en/content/articlepdf/2015/TB/C5TB00834D

Reference29 articles.

1. Mucoadhesive polymers in the design of nano-drug delivery systems for administration by non-parenteral routes: A review

2. Advances in Mucoadhesion and Mucoadhesive Polymers

3. Thiomers

4. Alginate–PEGAc: A new mucoadhesive polymer

5. Mollusk Glue Inspired Mucoadhesives for Biomedical Applications

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