Enantioselective modification of sulfonamides and sulfonamide-containing drugs via carbene organic catalysis-Reference-Cited by-同舟云学术

Enantioselective modification of sulfonamides and sulfonamide-containing drugs via carbene organic catalysis

Published:2021 Issue: Volume: Page:
ISSN:2052-4129
Container-title:Organic Chemistry Frontiers
language:en
Short-container-title:Org. Chem. Front.

Author:

Song Runjiang¹²³⁴⁵,Liu Yingguo¹²³⁴⁵,Majhi Pankaj Kumar¹²³⁴⁵,Ng Pei Rou¹²³⁴⁵,Hao Lin¹²³⁴⁵^ORCID,Xu Jun¹²³⁴⁵,Tian Weiyi⁶⁷⁸⁹,Zhang Long¹⁰¹¹¹²⁹,Liu Hongmei¹⁰¹¹¹²⁹^ORCID,Zhang Xinglong¹³¹⁴¹⁵¹⁶⁵^ORCID,Chi Yonggui Robin¹²³⁴⁵^ORCID

Affiliation:

1. Division of Chemistry & Biological Chemistry

2. School of Physical & Mathematical Science

3. Nanyang Technological University

4. Singapore 637371

5. Singapore

6. School of Pharmacy

7. Guizhou University of Traditional Chinese Medicine

8. Guiyang 550025

9. China

10. Institute of Nervous System Diseases

11. Xuzhou Medical University

12. Xuzhou 221002

13. Institute of High Performance Computing

14. A*STAR (Agency for Science

15. Technology and Research)

16. Singapore 138632

Abstract

Enantioselective modification of sulfonamides and sulfonamide-containing drugs via carbene organic catalysis is disclosed. The cation−π interaction was computationally found to play a pivotal role in modulating the reaction enantioselectivity.

Funder

National Research Foundation Singapore

Ministry of Education - Singapore

Agency for Science, Technology and Research

Nanyang Technological University

National Natural Science Foundation of China

Department of Education of Guizhou Province

Guizhou Science and Technology Department

Program for First-class Discipline Construction in Guizhou Province

Guizhou University

Publisher

Royal Society of Chemistry (RSC)