Low energy optical excitations as an indicator of structural changes initiated at the termini of amyloid proteins-Reference-Cited by-同舟云学术

Low energy optical excitations as an indicator of structural changes initiated at the termini of amyloid proteins

Published:2019 Issue:43 Volume:21 Page:23931-23942
ISSN:1463-9076
Container-title:Physical Chemistry Chemical Physics
language:en
Short-container-title:Phys. Chem. Chem. Phys.

Author:

Jong Kwang Hyok¹²³⁴⁵,Azar Yavar T.⁶⁷⁸⁹¹⁰^ORCID,Grisanti Luca⁵¹¹⁴¹²¹³^ORCID,Stephens Amberley D.¹⁴¹⁵¹⁶^ORCID,Jones Saul T. E.¹⁴¹⁵¹⁶^ORCID,Credgington Dan¹⁴¹⁵¹⁶^ORCID,Kaminski Schierle Gabriele S.¹⁴¹⁵¹⁶^ORCID,Hassanali Ali¹²³⁴^ORCID

Affiliation:

1. Condensed Matter and Statistical Physics

2. International Centre for Theoretical Physics

3. Trieste 34151

4. Italy

5. SISSA-Scuola Internazionale Superiore di Studi Avanzati

6. Physics and Accelerators School

7. NSTRI

8. AEOI

9. Tehran

10. Iran

11. Trieste 34136

12. Division of Theoretical Physics

13. Ruder Bošković Institute

14. Cavendish Laboratory, University of Cambridge

15. Cambridge CB3 0HE

16. UK

Abstract

We study the optical properties of amyloid aggregates relevant for neurodegenerative disease using experiments and computation. The low energy optical absorption in the near-UV range depends on conformations and involves charge-transfer excitations.

Funder

Royal Society

Publisher

Royal Society of Chemistry (RSC)

Subject

Physical and Theoretical Chemistry,General Physics and Astronomy

Link

http://pubs.rsc.org/en/content/articlepdf/2019/CP/C9CP04648H

Reference46 articles.

1. Protein Misfolding, Functional Amyloid, and Human Disease

2. Biology of Amyloid: Structure, Function, and Regulation

3. Computational Studies of Protein Aggregation: Methods and Applications