Synthesis of multisubstituted phenols by formal [4 + 2] cycloaddition of nucleophilic alkynes with 3-ethoxycyclobutanones-Reference-Cited by-同舟云学术

Synthesis of multisubstituted phenols by formal [4 + 2] cycloaddition of nucleophilic alkynes with 3-ethoxycyclobutanones

Published:2017 Issue:25 Volume:15 Page:5268-5271
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Kuzuguchi Takeo¹²³⁴⁵,Yabuuchi Yuto¹²³⁴⁵,Yoshimura Tomoyuki¹²³⁴⁵,Matsuo Jun-ichi¹²³⁴⁵^ORCID

Affiliation:

1. Division of Pharmaceutical Sciences

2. Graduate School of Medical Sciences

3. Kanazawa University

4. Kanazawa 920-1192

5. Japan

Abstract

Formal [4 + 2] cycloaddition between 3-ethoxycyclobutanones and nucleophilic alkynes proceeded to give multisubstituted phenols by using TiCl₄ as a Lewis acid.

Funder

Japan Society for the Promotion of Science

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C7OB00827A

Reference34 articles.

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2. Benzannulation

3. Recent Advances in the Transition-Metal-Catalyzed Regioselective Approaches to Polysubstituted Benzene Derivatives

4. Multi-component syntheses of heterocycles by transition-metal catalysis

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