A one-pot, multicomponent reaction for the synthesis of novel 2-alkyl substituted 4-aminoimidazo[1,2-a][1,3,5]triazines-Reference-Cited by-同舟云学术

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A one-pot, multicomponent reaction for the synthesis of novel 2-alkyl substituted 4-aminoimidazo[1,2-a][1,3,5]triazines

Published:2018 Issue:38 Volume:8 Page:21495-21504
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Lim Felicia Phei Lin¹²³^ORCID,Tan Lin Yuing¹²³^ORCID,Tiekink Edward R. T.⁴⁵⁶³,Dolzhenko Anton V.¹²³⁷⁸^ORCID

Affiliation:

1. School of Pharmacy

2. Monash University Malaysia

3. Malaysia

4. Research Centre for Crystalline Materials

5. School of Science and Technology

6. Sunway University

7. School of Pharmacy and Biomedical Sciences

8. Curtin Health Innovation Research Institute

Abstract

A highly selective, one-pot, three-component synthesis of novel 2-alkyl-substituted 4-aminoimidazo[1,2-a][1,3,5]triazines has been developed.

Funder

Ministry of Higher Education, Malaysia

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2018/RA/C8RA03703E

Reference61 articles.

1. A new microwave-assisted, three-component reaction of 5-aminopyrazole-4-carboxylates: Selective synthesis of substituted 5-aza-9-deaza-adenines

2. 1,3,5-Triazine-based analogues of purine: From isosteres to privileged scaffolds in medicinal chemistry

3. Design, Synthesis, and Evaluation of Novel Imidazo[1,2-a][1,3,5]triazines and Their Derivatives as Focal Adhesion Kinase Inhibitors with Antitumor Activity

4. Synthesis and optimization of substituted furo[2,3-d]-pyrimidin-4-amines and 7H-pyrrolo[2,3-d]pyrimidin-4-amines as ACK1 inhibitors

5. Comparison of different heterocyclic scaffolds as substrate analog PDE5 inhibitors

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5. Diversity-oriented synthesis of imidazo[1,2-a][1,3,5]triazine derivatives from 2-amine-[1,3,5]triazines with ketones;Chemical Communications;2021

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