Substrate elasticity modulates the responsiveness of mesenchymal stem cells to commitment cues
Author:
Affiliation:
1. Laboratory of Stem Cell Bioengineering (LSCB)
2. Institute of Bioengineering (IBI)
3. Ecole Polytechnique Fédérale de Lausanne (EPFL)
4. Lausanne
5. Switzerland
Abstract
Fate choices of stem cells are regulated in response to a complex array of biochemical and physical signals from their microenvironmental niche.
Publisher
Oxford University Press (OUP)
Subject
Biochemistry,Biophysics
Link
http://pubs.rsc.org/en/content/articlepdf/2015/IB/C4IB00176A
Reference27 articles.
1. Growth Factors, Matrices, and Forces Combine and Control Stem Cells
2. An algorithm-based topographical biomaterials library to instruct cell fate
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4. Matrix Elasticity Directs Stem Cell Lineage Specification
5. Stiffness Gradients Mimicking In Vivo Tissue Variation Regulate Mesenchymal Stem Cell Fate
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