Zn(OTf)2-mediated annulations of N-propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds-Reference-Cited by-同舟云学术

Zn(OTf)2-mediated annulations of N-propargylated tetrahydrocarbolines: divergent synthesis of four distinct alkaloidal scaffolds

Published:2019 Issue:22 Volume:10 Page:5686-5698
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Yorimoto Sadaiwa¹²³⁴⁵,Tsubouchi Akira¹²³⁴⁵,Mizoguchi Haruki⁶⁷⁸⁵,Oikawa Hideaki⁹¹⁰¹¹¹²⁵^ORCID,Tsunekawa Yoshiaki⁹¹⁰¹¹¹²⁵,Ichino Tomoya⁹¹⁰¹¹¹²⁵,Maeda Satoshi⁹¹⁰¹¹¹²⁵^ORCID,Oguri Hiroki¹²³⁴⁵^ORCID

Affiliation:

1. Department of Applied Chemistry

2. Graduate School of Engineering

3. Tokyo University of Agriculture and Technology

4. Koganei

5. Japan

6. Graduate School of Natural Science and Technology

7. Okayama University

8. Okayama 700-8530

9. Department of Chemistry

10. Faculty of Science

11. Hokkaido University

12. Sapporo 060-0810

Abstract

Experimental and computational studies gained insights into Zn(OTf)₂-mediated annulations and allowed programmable synthesis of four distinct alkaloidal scaffolds.

Funder

Japan Science and Technology Agency

Japan Society for the Promotion of Science

Astellas Foundation for Research on Metabolic Disorders

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2019/SC/C9SC01507H

Reference65 articles.

1. Hydroarylation of alkynes catalyzed by nickel