Synthesis of functionalized isoxazole–oxindole hybrids via on water, catalyst free vinylogous Henry and 1,6-Michael addition reactions-Reference-Cited by-同舟云学术

Synthesis of functionalized isoxazole–oxindole hybrids via on water, catalyst free vinylogous Henry and 1,6-Michael addition reactions

Published:2015 Issue:100 Volume:5 Page:81768-81773
ISSN:2046-2069
Container-title:RSC Advances
language:en
Short-container-title:RSC Adv.

Author:

Nagaraju Sakkani¹²³⁴,Satyanarayana Neeli¹²³⁴,Paplal Banoth¹²³⁴,Vasu Anuji K.¹⁵⁶⁴,Kanvah Sriram¹⁵⁶⁴,Kashinath Dhurke¹²³⁴

Affiliation:

1. Department of Chemistry

2. National Institute of Technology

3. Warangal-506004

4. India

5. Indian Institute of Technology

6. Ahmedabad

Abstract

Various isoxazole–oxindole hybrids were synthesized via vinylogous Henry reaction of 3,5-dimethyl-4-nitroisoxazole and isatin under catalyst free conditions in water. The products obtained were functionalized using 1,6-Michael addition reaction.

Funder

Science and Engineering Research Board

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemical Engineering,General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/RA/C5RA14039K

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1. Discovery of a Novel Class of Potent HCV NS4B Inhibitors: SAR Studies on Piperazinone Derivatives

2. Excitatory amino acid receptor ligands. Synthesis and biological activity of 3-isoxazolol amino acids structurally related to homoibotenic acid

3. Functional neuronal replacement by grafted striatal neurones in the ibotenic acid-lesioned rat striatum

4. Isoxicam and related 4-hydroxy-N-isoxazolyl-2H-1,2-benzothiazine-3-carboxamide, 1,1-dioxides. Potent nonsteroidal antiinflammatory agents

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