Microwave-assisted synthesis of the anticancer drug cisplatin, cis-[Pt(NH3)2Cl2]-Reference-Cited by-同舟云学术

Microwave-assisted synthesis of the anticancer drug cisplatin, cis-[Pt(NH3)2Cl2]

Published:2015 Issue:7 Volume:44 Page:3384-3392
ISSN:1477-9226
Container-title:Dalton Transactions
language:en
Short-container-title:Dalton Trans.

Author:

Petruzzella Emanuele¹²³⁴,Chirosca Cristian V.¹²³⁴,Heidenga Cameron S.¹²³⁴,Hoeschele James D.¹²³⁴

Affiliation:

1. Department of Chemistry

2. Eastern Michigan University

3. Ypsilanti

4. USA

Abstract

A rapid one-step microwave-assisted synthesis of cisplatin and two purification methods were developed. The process requires about 80 min and could be used to incorporate short-lived Pt radionuclides into cisplatin.

Publisher

Royal Society of Chemistry (RSC)

Subject

Inorganic Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2015/DT/C4DT03617D

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