Astaxanthin targets IL-6 and alleviates the LPS-induced adverse inflammatory response of macrophages

Author:

Wu Yahui12,Bashir Mona A.12,Shao Changsheng3,Wang Han12,Zhu Jianxia14,Huang Qing12ORCID

Affiliation:

1. CAS Key Laboratory of High Magnetic Field and Ion Beam Physical Biology, Anhui Key Laboratory of Environmental Toxicology and Pollution Control Technology, Hefei Institute of Intelligent Agriculture, Institute of Intelligent Machines, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China

2. Science Island Branch of Graduate School, University of Science & Technology of China, Hefei 230026, China

3. High Magnetic Field Laboratory, Hefei Institutes of Physical Science, Chinese Academy of Sciences, Hefei 230031, China

4. School of Nursing, Anhui Medical University, Hefei, Anhui 230032, China

Abstract

AST exerts anti-inflammatory effects and may target IL-6 to inhibit the positive feedback loop of inflammatory factors, thereby effectively reducing adverse inflammatory responses.

Funder

Hefei Institutes of Physical Science, Chinese Academy of Sciences

Publisher

Royal Society of Chemistry (RSC)

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