Biocompatibility studies on lanthanum oxide nanoparticles

Author:

Brabu B.12345,Haribabu S.12345,Revathy M.12345,Anitha S.6789,Thangapandiyan M.1011125,Navaneethakrishnan K. R.12345,Gopalakrishnan C.12345,Murugan S. S.12345,Kumaravel T. S.12345

Affiliation:

1. Nanotechnology Research Center and GLR Laboratories

2. Academic–Industry Joint Collaborative Research Unit

3. SRM University

4. Chennai

5. India

6. UNAM-National Nanotechnology Research Centre

7. Bilkent University

8. Ankara

9. Turkey

10. Department of Veterinary Pathology

11. Madras Veterinary College

12. Chennai 600007

Abstract

Biocompatibility on lanthanum oxide nanoparticles (LONP) were investigated. LONP was cytotoxic to balb/3T3 cells via release of ROS. LONP and/or extracts were non-irritant, non-sensitizer and non-mutagenic. LONP extracts did not show acute systemic toxicity. Whereas, LONP exerted hepatotoxicity following oral administration.

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

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