Nitrogen atom insertion into indenes to access isoquinolines-Reference-Cited by-同舟云学术

Nitrogen atom insertion into indenes to access isoquinolines

Published:2023 Issue:11 Volume:14 Page:2954-2959
ISSN:2041-6520
Container-title:Chemical Science
language:en
Short-container-title:Chem. Sci.

Author:

Finkelstein Patrick¹^ORCID,Reisenbauer Julia C.¹^ORCID,Botlik Bence B.¹^ORCID,Green Ori¹^ORCID,Florin Andri¹,Morandi Bill¹^ORCID

Affiliation:

1. Laboratorium für Organische Chemie, ETH Zürich, Vladimir-Prelog-Weg 3, HCI, 8093 Zürich, Switzerland

Abstract

We report a convenient protocol for a nitrogen atom insertion into indenes to afford isoquinolines. The strategy further enables the synthesis of pyridines from cyclopentadienes and a facile access to15N labelled isoquinolines.

Funder

Eidgenössische Technische Hochschule Zürich

Schweizerischer Nationalfonds zur Förderung der Wissenschaftlichen Forschung

European Commission

Publisher

Royal Society of Chemistry (RSC)

Subject

General Chemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2023/SC/D2SC06952K

Reference46 articles.

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3. Privileged scaffolds for library design and drug discovery

4. Local Anesthetics. Aminoalkoxyisoquinoline Derivatives

5. Synthesis, characterization and antimalarial activity of isoquinoline derivatives

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