Stereoisomers of oseltamivir – synthesis, in silico prediction and biological evaluation-Reference-Cited by-同舟云学术

Stereoisomers of oseltamivir – synthesis, in silico prediction and biological evaluation

Published:2017 Issue:8 Volume:15 Page:1828-1841
ISSN:1477-0520
Container-title:Organic & Biomolecular Chemistry
language:en
Short-container-title:Org. Biomol. Chem.

Author:

Hajzer Viktória¹²³⁴,Fišera Roman¹²³⁴,Latika Attila¹²³⁴,Durmis Július¹²³⁴,Kollár Jakub⁵⁶⁷⁸⁴,Frecer Vladimír⁵⁶⁹⁸⁴,Tučeková Zuzana¹⁰¹¹¹²¹³⁴,Miertuš Stanislav¹⁴¹⁵⁴¹⁰¹¹,Kostolanský František¹⁶¹⁷¹⁸¹⁹²⁰,Varečková Eva¹⁶¹⁷¹⁸¹⁹²⁰,Šebesta Radovan⁵¹¹²¹³⁴^ORCID

Affiliation:

1. SYNKOLA

2. Ltd

3. SK-84215 Bratislava

4. Slovakia

5. Comenius University in Bratislava

6. Faculty of Pharmacy

7. Department of Pharmaceutical Analysis and Nuclear Pharmacy

8. SK-83232 Bratislava

9. Department of Physical Chemistry of Drugs

10. University of SS. Cyril and Methodius

11. Faculty of Natural Sciences

12. Department of Biotechnologies

13. SK-91701 Trnava

14. ICARST n.o.

15. SK-84104 Bratislava

16. Biomedical Research Center

17. Institute of Virology

18. Slovak Academy of Sciences

19. Department of Orthomyxovirus Research

20. SK-84505 Bratislava

21. Department of Organic Chemistry

Abstract

Three diastereoisomers of oseltamivir were synthesized, their properties predicted by quantum-chemical calculations and their antiviral activities evaluated.

Funder

Agentúra na Podporu Výskumu a Vývoja

Agentúra Ministerstva školstva, vedy, výskumu a športu SR

Publisher

Royal Society of Chemistry (RSC)

Subject

Organic Chemistry,Physical and Theoretical Chemistry,Biochemistry

Link

http://pubs.rsc.org/en/content/articlepdf/2017/OB/C6OB02673G

Reference51 articles.

1. WHO , Influenza (Seasonal), Fact sheet No. 211, 2014

2. WHO , Model List of Essential Medicines, 19th list edn, 2015, p. http://www.who.int/medicines/publications/essentialmedicines/en/index.html