Protein cross-linking capillary electrophoresis at increased throughput for a range of protein–protein interactions

Author:

Ouimet Claire M.1234,Dawod Mohamed1234,Grinias James12341,Assimon Victoria A.564,Lodge Jean1234,Mapp Anna K.12347,Gestwicki Jason E.564,Kennedy Robert T.12348ORCID

Affiliation:

1. Department of Chemistry

2. University of Michigan

3. Ann Arbor

4. USA

5. Department of Pharmaceutical Chemistry

6. University of California at San Francisco

7. Program in Chemical Biology

8. Department of Pharmacology

Abstract

Here protein cross-linking capillary electrophoresis is demonstrated for a wide range of protein–protein interactions including weak and multimeric oligomers.

Funder

National Institutes of Health

Eli Lilly and Company

Publisher

Royal Society of Chemistry (RSC)

Subject

Electrochemistry,Spectroscopy,Environmental Chemistry,Biochemistry,Analytical Chemistry

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