Transcriptomic alterations induced by Monuron in rat and human renal proximal tubule cells in vitro and comparison to rat renal-cortex in vivo

Author:

Bloch Katarzyna M.1234,Yaqoob Noreen1234,Sharma Sikander1234,Evans Andrew1234,Aschauer Lydia56789,Radford Robert1011121314,Jennings Paul56789,Ryan Michael P.1011121314,van Delft Joost H. M.1516171819,Lock Edward A.1234

Affiliation:

1. School of Pharmacy and Biomolecular Sciences

2. Liverpool John Moores University

3. Liverpool

4. UK

5. Division of Physiology

6. Department of Physiology and Medical Physics

7. Innsbruck Medical University

8. Innsbruck

9. Austria

10. Renal Disease Research Group

11. School of Biomolecular and Biomedical Science

12. UCD Conway Institute

13. University College Dublin

14. Ireland

15. Department of Health Risk Analyses and Toxicology

16. Faculty of Health

17. Medicine and Life Sciences

18. Maastricht University

19. Maastricht

Abstract

Monuron (1,1-dimethyl-3-(4-chlorophenyl)urea) is a widely used herbicide in developing countries although concerns have been raised about its toxicity and carcinogenicity.

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Reference36 articles.

1. A study of the mode of action of 3-(4-chlorophenyl)-i,i-dimethylurea on photosynthesis

2. NTP , National Toxicology Program technical report series, 1988, 266, 1166

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