New approaches to advance the use of genetic toxicology analyses for human health risk assessment-Reference-Cited by-同舟云学术

New approaches to advance the use of genetic toxicology analyses for human health risk assessment

Published:2015 Issue:3 Volume:4 Page:667-676
ISSN:2045-452X
Container-title:Toxicology Research
language:en
Short-container-title:Toxicol. Res.

Author:

Johnson George E.¹²³⁴⁵,Slob Wout¹²³⁴⁵,Doak Shareen H.¹²³⁴⁵,Fellows Mick D.⁶⁷⁸⁵,Gollapudi Bhaskar B.⁹¹⁰¹¹¹²,Heflich Robert H.¹³¹⁴¹⁵¹²,Rees Ben J.¹²³⁴⁵,Soeteman-Hernández Lya G.¹⁶¹⁷¹⁸¹⁹,Verma Jatin R.¹²³⁴⁵,Wills John W.¹²³⁴⁵,Jenkins Gareth J. S.¹²³⁴⁵,White Paul A.²⁰²¹²²²³²⁴

Affiliation:

1. Institute of Life Science

2. College of Medicine

3. Swansea University

4. Swansea

5. UK

6. Discovery Safety

7. AstraZeneca

8. Cambridge

9. Center for Toxicology and Mechanistic Biology

10. Exponent

11. Midland

12. USA

13. National Centre for Toxicological Research

14. U.S. Food and Drug Administration

15. Jefferson

16. Center for Health Protection

17. National Institute for Public Health and the Environment (RIVM)

18. Bilthoven

19. Netherlands

20. Environmental Health Sciences and Research Bureau

21. Healthy Environments and Consumer Safety Branch

22. Health Canada

23. Ottawa

24. Canada

Abstract

Genetic toxicology testing has a crucial role in the safety assessment of substances of societal value by reducing human exposure to potential somatic and germ cell mutagens.

Funder

Health Canada

Engineering and Physical Sciences Research Council

National Centre for the Replacement, Refinement and Reduction of Animals in Research

Publisher

Oxford University Press (OUP)

Subject

Health, Toxicology and Mutagenesis,Toxicology

Link

http://pubs.rsc.org/en/content/articlepdf/2015/TX/C4TX00118D

Reference49 articles.

1. Follow-up actions from positive results of in vitro genetic toxicity testing